Mild intermittent hypoxia exposure induces metabolic and molecular adaptations in men with obesity.

Objective: Recent studies suggest that hypoxia exposure may improve glucose homeostasis, but well-controlled human studies are lacking. We hypothesized that mild intermittent hypoxia (MIH) exposure decreases tissue oxygen partial pressure (pO) and induces metabolic improvements in people who are overweight/obese.

Methods: In a randomized, controlled, single-blind crossover study, 12 men who were overweight/obese were exposed to MIH (15 % O, 3 × 2 h/day) or normoxia (21 % O) for 7 consecutive days.

Validity and reproducibility of VO max testing in a respiration chamber.

The aim of this study was to investigate whether VO max can be accurately measured in a respiration chamber. Thirty participants aged 23.4 ± 3.

Room Indirect Calorimetry Operating and Reporting Standards (RICORS 1.0): A Guide to Conducting and Reporting Human Whole-Room Calorimeter Studies.

Whole-room indirect calorimeters have been used to study human metabolism for more than a century. These studies have contributed substantial knowledge to the assessment of nutritional needs and the regulation of energy expenditure and substrate oxidation in humans. However, comparing results from studies conducted at different sites is challenging because of a lack of consistency in reporting technical performance, study design, and results.

Test-retest variability of VO using total-capture indirect calorimetry reveals linear relationship of VO and Power.

This study aimed to analyze the intra-individual variation in VO of human subjects using total-capture and free-flow indirect calorimetry. Twenty-seven men (27 ± 5 year; VO 49-79 mL•kg •min ) performed two maximal exertion tests (CPETs) on a cycle ergometer, separated by a 7 ± 2 day interval. VO and VCO were assessed using an indirect calorimeter (Omnical) with total capture of exhalation in a free-flow airstream.