Publications by authors named "P F Dequin"
Can Biomarkers Correctly Predict Ventilator-associated Pneumonia in Patients Treated With Targeted Temperature Management After Cardiac Arrest? An Exploratory Study of the Multicenter Randomized Antibiotic (ANTHARTIC) Study.
Nicolas Deye Amelie Le Gouge Bruno François Camille Chenevier-Gobeaux Thomas Daix Pierre-François Dequin
Crit Care Explor
July 2024
Article Synopsis
- - Ventilator-associated pneumonia (VAP) is common in cardiac arrest patients, but diagnosing it post-arrest is difficult, leading to debate over the effectiveness of biomarkers like C-reactive protein (CRP) and procalcitonin (PCT) for this purpose.
- - The study analyzed the role of various biomarkers in diagnosing and predicting VAP within 48 hours following cardiac arrest and therapeutic hypothermia, using a randomized clinical trial as a foundation.
- - Results showed that VAP patients had distinct clinical features and higher biomarker levels indicating VAP; CRP was notably associated with VAP, demonstrating an area under the curve (AUC) greater than 0.70 in analyses.
Introduction: New beta-lactams, associated or not with beta-lactamase inhibitors (NBs/BIs), can respond to the spread of carbapenemase-producing enterobacteriales and nonfermenting carbapenem-resistant bacteria. The risk of emergence of resistance to these NBs/BIs makes guidelines necessary. The SRLF organized a consensus conference in December 2022.
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