Publications by authors named "P Erba"
Fibrosis is one of the key healing responses to injury, especially within the heart where it helps to maintain structural integrity following acute insults such as myocardial infarction. However, if it becomes dysregulated then fibrosis can become maladaptive leading to adverse remodelling, impaired cardiac function and heart failure. Fibroblast activation protein is exclusively expressed by activated fibroblasts, the key effector cells of fibrogenesis, and has a unique extracellular domain that is an ideal ligand for novel molecular imaging probes.
View Article and Find Full Text PDFA cutting-edge technology for the future of nuclear medicine.
Eur J Nucl Med Mol Imaging
February 2025
Current and Emerging Radiotracers in Molecular Cardiovascular Imaging.
Circ Cardiovasc Imaging
October 2024
Article Synopsis
- Cardiovascular imaging has evolved significantly, with traditional methods like echocardiography and CT scans essential for assessing heart structure and function, but often lacking direct insights into disease activity.
- Molecular nuclear imaging techniques, such as PET and SPECT, are bridging this gap by allowing visualization of disease processes at a molecular and cellular level.
- The review emphasizes how advancements in molecular imaging are crucial for precision medicine, aiding in better understanding of diseases, developing targeted treatments, and personalizing patient care.