Publications by authors named "P E Shevchuk"
Article Synopsis
- Ukraine's unique socio-economic and political landscape, along with its historical diversity, provides valuable insights into mortality trends in Eastern Europe between 2006 and 2019.
- The analysis highlights a significant decline in mortality differences across regions, particularly noting that cardiovascular disease is a major factor behind these disparities, especially among older females.
- Despite progress, mortality from external causes has decreased, while issues like suicide, HIV, and lung cancer remain concentrated in specific areas, warranting further investigation into the underlying factors.
Review. Modern data about mechanisms of generation of the calcium signals in the exocrine acinar cells are presented. The mechanisms of inositol-1,4,5-trisphosphate- and Ca(2+)-induced Ca2+ release from intracellular stores of the acinar cells and mechanisms their influx from extracellular medium are described.
View Article and Find Full Text PDFThe action of pharmacological drugs (caffeine, procaine, ruthenium red) which influenced the release of Ca2+ from endoplasmatic reticulum, the electrical responses of dog pancreatic acinar cells was investigated using intracellular glass microelectrodes. These drugs were used to elucidate the mechanisms of Ca2+ release from endoplasmatic reticulum. Membrane depolarization and decrease of input resistance were observed in the presence of caffeine.
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