From orogeny to rifting: insights from the Norwegian 'reactivation phase'.

Based on observations from the Mid-Norwegian extensional system, we describe how, when and where the post-Caledonian continental crust evolved from a context of orogenic disintegration to one of continental rifting. We highlight the importance of a deformation stage that occurred between the collapse mode and the high-angle faulting mode often associated with early rifting of continental crust. This transitional stage, which we interpret to represent the earliest stage of rifting, includes unexpected large magnitudes of crustal thinning facilitated through the reactivation and further development of inherited collapse structures, including detachment faults, shear zones and metamorphic core complexes.

Complex fault interaction controls continental rifting.

Rifted margins mark a transition from continents to oceans and contain in their architecture a record of their rift history. Recent investigations of rift architecture have suggested that multiphase deformation of the crust and mantle lithosphere leads to the formation of distinct margin domains. The processes that control transitions between these domains, however, are not fully understood.

Primary Paget's disease of the penis. Case report.

A 64-year-old man presented to the dermatology clinic with primary genital Paget's disease. He was treated conservatively and died of metastases nine years later. The natural history of the lesion is malignant, and radical excision is recommended.

Clinical patch test data evaluated by multivariate analysis. Danish Contact Dermatitis Group.

The aim of the present study was to evaluate the influence of individual explanatory factors, such as sex, age, atopy, test time and presence of diseased skin, on clinical patch test results, by application of multivariate statistical analysis. The study population was 2166 consecutive patients patch tested with the standard series of the International Contact Dermatitis Research Group (ICDRG) by members of the Danish Contact Dermatitis Group (DCDG) over a period of 6 months. For the 8 test allergens most often found positive (nickel, fragrance-mix, cobalt, chromate, balsam of Peru, carba-mix, colophony, and formaldehyde), one or more individual factors were of significance for the risk of being sensitized, except for chromate and formaldehyde.