Publications by authors named "P E Heudel"

Background: Paraneoplastic inflammatory syndrome (PIS) with fever and biological inflammation is a rare but severe condition often caused by the systemic production of interleukin 6 (IL-6) by cancer cells. We report on the efficacy of tocilizumab, an anti-IL-6 receptor antibody, in 35 patients with severe PIS.

Patients And Methods: All 35 patients with solid cancers (sarcomas, lung carcinoma, and breast carcinoma) diagnosed with a PIS from 2019 to 2024 treated with tocilizumab were analyzed in this single-center study (health authorities' approval R201-004-478).

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Article Synopsis
  • Therapeutic compliance in oncology is vital for effective cancer treatment, yet traditional methods to improve adherence like patient education have limited success.
  • This review explores how digital health technologies, such as mHealth apps and telemedicine, can enhance adherence by providing features like medication reminders and continuous care.
  • While these technologies show promise in improving patient engagement and treatment compliance, challenges such as data privacy and the need for personalized approaches must be tackled in future research.
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Introduction: The importance of body composition and sarcopenia is well-recognized in cancer patient outcomes and treatment tolerance, yet routine evaluations are rare due to their time-intensive nature. While CT scans provide accurate measurements, they depend on manual processes. We developed and validated a deep learning algorithm to automatically select and segment abdominal muscles [SM], visceral fat [VAT], and subcutaneous fat [SAT] on CT scans.

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Importance: Oral endocrine treatments have been shown to be effective when carefully adhered to. However, in patients with early breast cancer, adherence challenges are notable, with 17% experiencing nonpersistence and 41% nonadherence at least once.

Objective: To model the persistence of and adherence to oral anticancer treatment of a patient with localized breast cancer.

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