Synthesis, mixed-spin-state structure and Langmuir-Blodgett deposition of amphiphilic Fe(iii) quinolylsalicylaldiminate complexes.

Designing and integrating Fe(iii)-based spin crossover (SCO) complexes onto substrates remains a challenging goal with only a handful of examples reported. In this work, we successfully synthesized and characterized three [Fe(qsal-OR)]NO (qsal-OR = 5-alkoxy-2-[(8-quinolylimino)methyl]phenolate) complexes, in which R = CH1, CH2, and CH3 to explore the impact of alkyl chain on the modulation of SCO activity and potential for self-assembly on a glass surface. The SCO is found to be gradual and incomplete in all cases, with the LS state more stabilised as the alkyl group shortens.

Controlled Release of Molecules to Enhance Cell Survival and Regeneration.

Controlled release or controlled drug delivery comprises the set of techniques and approaches to improve bioavailability through improved safety and/or efficacy using a carrier material for the molecule of interest. The predictability and tunability of these carriers make them ideal for protection, localization, and sustained presentation of a wide range of therapeutics, including growth factors implicated in cell survival and regeneration. Here we provide a method for encapsulating epidermal growth factor in a degradable polymer matrix for delivery to the cornea.

Thermal Jahn-Teller Distortion Changes and Slow Relaxation of Magnetization in Mn(III) Schiff Base Complexes.

The impact that the anion and alkyl group has on the electronic structures and magnetic properties of four mononuclear Mn(III) complexes is explored in [Mn(salEen-Br)]Y (salEen-Br = 2-{[2-(ethylamino)ethylimino]methyl}-4-Br-phenol; Y = ClO and BF·1/3CHCl ) and [Mn(salBzen-Br)]Y (salBzen-Br = 2-{[2-(benzylamino)ethylimino]methyl}-4-Br-phenol; Y = ClO and BF ). X-ray structures of [Mn(salEen-Br)]ClO·0.45CH , [Mn(salEen-Br)]BF·0.

Antibacterial and antibiofilm efficacy of Solanum lasiocarpum root extract synthesized silver/silver chloride nanoparticles against Staphylococcus haemolyticus associated with bovine mastitis.

Staphylococcus haemolyticus is a cause of bovine mastitis, leading to inflammation in the mammary gland. This bacterial infection adversely affects animal health, reducing milk quality and yield. Its emergence has been widely reported, representing a significant economic loss for dairy farms.

Disruption of common ocular developmental pathways in patient-derived optic vesicle models of microphthalmia.

Genetic perturbations influencing early eye development can result in microphthalmia, anophthalmia, and coloboma (MAC). Over 100 genes are associated with MAC, but little is known about common disease mechanisms. In this study, we generated induced pluripotent stem cell (iPSC)-derived optic vesicles (OVs) from two unrelated microphthalmia patients and healthy controls.