Transcriptomic changes in oxidative stress, immunity, and cancer pathways caused by cannabis vapor on alveolar epithelial cells.

As legalization of cannabis increases worldwide, vaping cannabis is gaining popularity due to the belief that it is less harmful than smoking cannabis. However, the safety of cannabis vaping remains untested. To address this, we developed a physiologically relevant method for in vitro assessment of cannabis vapor on alveolar epithelial cell cultures.

Extracellular vesicle biomarkers redefine prostate cancer radiotherapy.

Radiotherapy (RT) remains a cornerstone in the treatment of prostate cancer (PCa). Extracellular vesicles (EVs), nano-sized particles secreted by cells, play important roles in intercellular communication within the tumour microenvironment (TME) and contribute to tumour growth, metastasis, and therapy resistance. Recent advancements demonstrate the potential of EVs as biomarkers for cancer diagnosis, prognosis, and treatment monitoring.

The neuroethology of ant navigation.

Unlike any other group of animals, all ant species are social: individual ants share the food they gather with their nestmates and as a consequence they must repeatedly leave their nest to find food and then return home with it. These back-and-forth foraging trips have been studied for about a century and much of our growing understanding of the strategies underlying animal navigation has come from these studies. One important strategy that ants use to keep track of where they are on a foraging trip is 'path integration', in which they continuously update a 'home vector' that gives their estimated distance and direction from the nest.

Child mental health problems and poverty.

Waiting lists for children and young people with mental health problems are at an all-time high. Almost the only policies proposed to deal with this situation involve increasing the number of mental health professionals. Little attention is given to dealing with the underlying causative stresses, of which poverty is easily the most pervasive.