Publications by authors named "P E Carlson"
Article Synopsis
- * A macroinvertebrate-based multimetric index (MMI) was created for both the pelagic and littoral zones of Lake Hongze to assess ecological health, revealing a "poor" status for the pelagic zone and a "fair" status for the littoral zone.
- * Key environmental factors affecting the ecological health included sediment organic matter for the pelagic zone, and chlorophyll a and transparency for the littoral zone, with functional feeding groups showing high sensitivity to disturbances in both areas.
Bacteriophage therapy is a promising approach to address antimicrobial infections though questions remain regarding the impact of the immune response on clinical effectiveness. Here, we develop a mouse model to assess phage treatment using a cocktail of five phages from the Myoviridae and Siphoviridae families that target Vancomycin-Resistant Enterococcus gut colonization. Phage treatment significantly reduces fecal bacterial loads of Vancomycin-Resistant Enterococcus.
View Article and Find Full Text PDFFecal microbiota transplantation (FMT) has been demonstrated to be efficacious in preventing recurrent Clostridioides difficile (C. difficile) infections, and is being investigated for treatment of several other diseases including inflammatory bowel disease, cancer, obesity, liver disease, and diabetes. To speed up the translation of FMT into clinical practice as a safe and standardized therapeutic intervention, additional evidence-based technical and regulatory guidance is needed.
View Article and Find Full Text PDFWords or code first? Is the legacy document or a code statement the better starting point for complexity-reducing legal automation?
Philos Trans A Math Phys Eng Sci
April 2024
Law is a critical tool that humans have created to assist them in managing complex social interactions. Computational Law holds the potential to significantly enhance our capacity to express and manage legal complexity, and a number of advantages can result from restating public and private legal rules in computable form. Capturing that potential depends in part on the approaches taken to automation.
View Article and Find Full Text PDFBackground: The COVID-19 pandemic encouraged telemedicine expansion. Research regarding follow-up healthcare utilization and primary care (PC) telemedicine is lacking.
Objective: To evaluate whether healthcare utilization differed across PC populations using telemedicine.