Publications by authors named "P Dwarkanath"
Impact of nutritional and multiple micronutrients supplementation to lactating mothers 6 months postpartum on the maternal and infant micronutrient status: a randomised controlled trial in Delhi, India.
Public Health Nutr
September 2024
Article Synopsis
- The study looked at how giving extra nutrition and vitamins to breastfeeding mothers affects both the mothers and their babies after 6 months.
- Mothers who received special snacks and vitamin tablets showed more vitamins and nutrients in their blood compared to those who didn't.
- The results also showed that their babies had higher levels of important nutrients, suggesting that helping moms with nutrition can benefit both moms and their babies' health.
Neonate responses to pathogen-associated molecular patterns (PAMPS) differ from adults; such understanding is poor in Indian neonates, despite recognized significant infectious risk. Immune profiling analysis was undertaken of 10 secreted mediators contextualized with cellular source induced by six PAMPs in umbilical cord (CB; n = 21) and adult-blood (PBMC; n = 14) from a tertiary care hospital in South India. Differential cytokine expression analysis (minimum log2-fold difference; adj P-value < 0.
View Article and Find Full Text PDFBackground: The World Health Organization recommends 1500 to 2000 mg of calcium daily as supplementation, divided into three doses, for pregnant persons in populations with low dietary calcium intake in order to reduce the risk of preeclampsia. The complexity of the dosing scheme, however, has led to implementation barriers.
Methods: We conducted two independent randomized trials of calcium supplementation, in India and Tanzania, to assess the noninferiority of a 500-mg daily dose to a 1500-mg daily dose of calcium supplementation.
Background: Human milk provides essential nutrition for infants, and its benefits are well established. We lack data on the influence of maternal nutritional status on milk volume and composition in low-middle income countries.
Objective: We aimed to 1) assess lactation performance (human milk volume, macronutrient composition, and infant energy intake) in Indian females and 2) examine the associations between maternal anthropometry (BMI, percentage body fat) and lactation performance.
Article Synopsis
- This study explored whether prior revaccination with the BCG vaccine enhances immune responses from the COVISHIELD™ COVID-19 vaccine in a group of young adults in India.
- Results showed that participants who received BCG revaccination exhibited significantly higher levels of antibodies and T-cells for eight months after receiving COVISHIELD™, compared to those who did not receive BCG revaccination.
- The enhanced immune response was linked to increased markers of trained immunity and epigenetic changes, providing evidence that BCG could effectively boost the immune response to current and future COVID-19 vaccines.