PvuII and XbaI polymorphisms of the estrogen receptor gene and bone mineral density in a Bulgarian population sample.

Objective: The aim of this study was to search for a possible association of low bone mineral density (bMD) with the PvuII and XbaI polymorphisms of the estrogen receptor (Er) gene in bulgarian women.

Design: 400 bulgarian women participated in this study. bMD was measured at the lumbar spine, femoral neck and at the distal forearm.

FokI and BsmI polymorphisms of the vitamin D receptor gene and bone mineral density in a random Bulgarian population sample.

Numerous studies on vitamin D receptor (VDR) gene polymorphisms differ with conflicting data in various populations. We studied the association of FokI and BsmI polymorphisms in the gene encoding the vitamin D receptor with bone mineral density (BMD) in 219 persons of Bulgarian nationality. The calculated relative risk (RR) for low bone mineral density is higher for FokI marker (3.

Effect of risedronate on bone metabolism after total hip arthroplasty: a prospective randomised study.

Aseptic loosening due to bone remodeling and osteolysis is the main reason for revision hip arthroplasty. At present, there is no established prophylaxis for this complication. On the other hand, it has been demonstrated that bisphosphonates prevent bone loss around total hip arthroplasties (THA).