Long-term immunity after vaccination against tick-borne encephalitis with Encepur using the rapid vaccination schedule.

148 of 157 invited adult subjects who had participated in previous studies were enrolled in this extension study for evaluation of immunogenicity and safety of the second TBE booster immunization. All subjects had been previously immunized in studies with Chiron's formerly marketed TBE vaccine (containing polygeline as the stabilizer) according to the rapid vaccination schedule (i.e.

[Serologic detection of hantavirus antibodies].

Within the framework of diagnosis of highly dangerous infections in the Army of the Czech Republic serological assessment of hantaviral antibodies was introduced. Because military units in the field can be in contact with sources of hantaviral infections, the authors investigated this population sample. In 1999-2000 a total of 542 healthy subjects were examined (age 20-40 years).

[Epidemiologic problems in hantavirus infections].

The objective of the submitted paper was to present some information pertaining to epidemiological problems of hantavirus infection. In the Czech Republic the prevalence of these infections is not alarming but in the world cases of haemorrhagic fever with renal syndrome (HFRS) as well as hantavirus pulmonary syndrome (HPS) are reported. On the territory of the Czech Republic there are foci of hantaviruses and in conjunction with summer tourism or working activities abroad the import of this infection cannot be ruled out.

Seroprevalence of viral hepatitis A in the Czech Republic.

Over recent decades, the epidemiology of hepatitis A has changed in most European countries: the age of infection has been shifting towards older age groups. In view of this evolution and the central location of the Czech Republic in Europe, we wanted to assess current anti-hepatitis A seroprevalence. We determined the anti-hepatitis A seroprevalence among three different groups: military personnel between 1991-1995, prior to their deployment as UN troops, civilians participating in a national serological survey in 1996 and volunteers for vaccine clinical trials in 1996.

[Long-term monitoring of Neisseria meningitidis carrier state in the nasopharynx and seroprevalence of specific antibodies in immunized and non-immunized persons].

Long-term (three-month and one-year) follow-up of nasopharyngeal carriers of Neisseria meningitidis with a frequency of sample collection of once a week and once a month resp. in the healthy population with a mean age of 43 years revealed a 4.8% positivity (2 of 42 subjects).