Publications by authors named "P Diez"
Optimal Sample Preparation Workflow for Quantitative Mass Spectrometry-Based Studies in the Low Range.
Methods Mol Biol
December 2024
Mass spectrometry (MS) enables the high-throughput characterization of thousands of proteins in one single run. Nowadays, advances in the field have allowed for deep analysis of low cell numbers, even reaching the single-cell level. However, standardized protocols are still needed in this regard, especially oriented for non-proteomics specialists.
View Article and Find Full Text PDFBackground: Locally advanced cervical cancer is treated with chemoradiotherapy (standard of care), but many patients still relapse and die from metastatic disease. We investigated chemoradiotherapy with or without induction chemotherapy to determine whether induction chemotherapy improves both progression-free survival and overall survival.
Methods: The INTERLACE trial was a multicentre, randomised phase 3 trial done at 32 medical centres in Brazil, India, Italy, Mexico, and the UK.
Article Synopsis
- Beetle infestations, specifically by Carpophilus truncatus and Oryzaephilus mercator, negatively impact walnut yield and quality by exposing them to harmful microbes like Fusarium species.
- This research focuses on creating eco-friendly copper oxide nanoparticles using plant extracts from Lippia integrifolia (CuO-I) and Pimpinella anisum (CuO-A), which were found to be effective against pests and harmful fungi.
- Characterization techniques revealed that these nanoparticles are small (2-10 nm) and exhibit strong antifungal and insecticidal properties, suggesting they could be viable alternatives for pest control in walnut storage.
Article Synopsis
- The study introduces a new preclinical device that uses Torsional Wave Elastography (TWE) to measure the stiffness of elastic materials and soft tissues.
- The device consists of a rotational actuator and a piezoceramic receiver, allowing shear waves to interact with tissue before being collected for analysis.
- Experimental tests showed that the device provides reliable, accurate stiffness measurements, with over 95% correlation to established techniques, suggesting potential for medical applications, especially in studying cervical properties during pregnancy.