[The treatment of ketoacidosis in children and adolescents with diabetes (simultaneous major ketosis and severe hypoglycemia)].

Ketoacidosis in pediatric diabetes mellitus remains an active problem. Although the authors have recorded no deaths among their own patients, fatal cases still occur in France and other countries, usually as a result of inappropriate therapy, sometimes based on mistaken immediate pathophysiologic interpretations of laboratory test results. A very simple protocol based on the author's extensive experience is proposed.

[Permanent malabsorption of rifampicin in a diabetic with celiac disease].

A 14 year-old boy with coeliac disease and poorly treated diabetes mellitus and pulmonary tuberculosis due to INH resistant BK presented with a permanent malabsorption of rifampicin. Pharmacokinetics of rifampicin was studied after oral administration and intravenous injection. Treatment of diabetes and coeliac disease did not improve the situation.

[Renal diabetes. Apropos of 103 cases].

Three main concepts came out of this prospective study of 103 cases (51 girls and 52 boys) of renal diabetes followed up from 1955 to 1975 and reviewed in 1984: contrary to what is still sometimes written, renal diabetes does not evolve to diabetes mellitus; renal diabetes does not seem to progress over the years; the mode of genetic transmission, when present, which is rare, is obscure but it seems to occur in a recessive rather than a dominant fashion.

[Glomerular filtration and tubular reabsorption of glucose in insulin-dependent diabetes in children].

Although glycosuria is important in the control of diabetes in children, few studies clearly show its significance as compared to glycemia. The aim of the present study was therefore to determine the two parameters that control glucose presence in urine, i.e.