This book chapter presents the most important clinical aspects concerning the gonadotropin-releasing hormone antagonist cetrorelix and its importance in reproductive medicine. After an overview of the historical milestones in the development and establishment of cetrorelix in the context of ovarian stimulation treatment, its dosage, effects, and side effects are evaluated. The chapter terminates with a conclusion emphasizing the ease of use and the increase in patient safety because of a significantly reduced risk of ovarian hyperstimulation syndrome with cetrorelix compared with the agonist protocol.
View Article and Find Full Text PDFBackground/objective: To reproduce the methods and results of the study by Alobeid et al. (2018) in which the efficacy of tooth alignment using conventional labial and lingual orthodontic bracket systems was assessed.
Materials/methods: We used the identical experimental protocol and tested (i) regular twin bracket (GAC-Twin [Dentsply]) and lingual twin bracket systems (Incognito [3M]), (ii) together with NiTi 0.
Aim: To analyze the spectrum of indications for second-generation palatal implants in relation to two different loading concepts in a prospective, multicenter, randomized controlled trial (RCT).
Patients And Methods: Forty-one patients were recruited to the study from 2006 to 2009. All implants (Orthosystem, Straumann, Basel, Switzerland; dimensions: 4.
This study aims to analyze the clinical performance of two loading concepts on second-generation palatal implants (Orthosystem, Straumann, Basel, Switzerland) in a prospective multicenter randomized controlled clinical trial. At the time of this interim analysis, 41 patients have been randomized on a 1:1 basis to one of two treatment groups. Group 1 underwent conventional loading of palatal implants after a healing period of 12 weeks (gold standard) while group 2 underwent immediate implant loading within 1 week after implant insertion.
View Article and Find Full Text PDFObjective: The aim of this clinical trial was to investigate and compare outcomes after treating a skeletal Class II malocclusion with two fixed functional orthodontic appliances, the Herbst appliance and the Functional Mandibular Advancer, by evaluating their skeletal and dentoalveolar effects and the repercussion on the profile in relation to patient age.
Patients And Methods: The sample population comprised 42 subjects with skeletal Class II malocclusion. They were divided into two groups depending on age.