Antithrombin III Avranches, a new variant with defective serine-protease inhibition--comparison with antithrombin III Charleville.

A decreased plasma antithrombin activity in presence or in absence of heparin was discovered in a 47-year-old patient presenting with recurrent venous thromboembolism. The immunoreactive material (AT III-IR) was normal. The same biological abnormalities were found in two relatives of the patient, leading to the diagnosis of hereditary qualitative AT III deficiency.

[Lipids and lipoproteins in atherosclerotic arteriopathy of the legs. Unusual study of very low density lipoproteins].

Lipids, apolipoproteins A1 and B and lipoproteins were studied in 49 patients with peripheral arterial disease and in 26 control patients. The observed hypertriglyceridemia was related to the elevation of the VLDL lipid mass; no alteration in their structure could be shown. The origin of this VLDL excess was discussed especially the role of tobacco and genetic.

[Subungual glomus tumor. Apropos of a case].

Glomus tumors are rare, though not exceptional. They are considered by some authors as hyperplasia of a normal neuromyo-arterial glomus, by others as a benign tumoral proliferation. Most of them combine the three histological types initially described by Masson.

[Value of arteriography in the exploration of subungual glomus tumors. Apropos of a case].

Difficulties in the diagnosis of subungual glomus tumors are increased when clinical examination and standard radiographic images are normal. In these cases arteriography is a useful procedure, opacification in the arterial phase of a small vascular lake confirming the diagnosis and localizing the lesion. A case is described that illustrates the interest of this examination, although it is indispensable only in patients with glomus tumors of atypical clinical expression or when symptoms recur after excision.