Swirl Sign in Intracerebral Hemorrhage.

An 80-year-old male (patient A) felt at home and consequently was admitted to the emergency unit. Following the head trauma, he was bleeding on the right frontoparietal area. The patient was found unconscious and the Glasgow Coma Scale was 9/15.

IDH1 mutation, a genetic alteration associated with adult gliomatosis cerebri.

Recently, mutations in IDH1 and IDH2 have been reported as an early and common genetic alteration in diffuse gliomas, being possibly followed by 1p/19q loss in oligodendrogliomas and TP53 mutations in astrocytomas. Lately, IDH1 mutations have also been identified in adult gliomatosis cerebri (GC). The aim of our study was to test the status of IDH1/2, p53 and of chromosomes 1 and 19 in a series of 12 adult and three pediatric GC.

Gliomatosis cerebri, imaging findings of 12 cases.

Background And Purpose: We report 12 cases of Gliomatosis cerebri (GC), a rare brain neoplasm, to define its semeiologic criteria. Literature was reviewed to clarify its physiopathology.

Patients And Methods: From 1997 to 2008, 12 histologically proven cases with GC were retrospectively reviewed.