[Drug hypersensitive syndrome caused by fluindione].

Background: Fluindione (Previscan) is an oral anticoagulant prescribed in relay to heparin therapy for deep venous thrombosis, pulmonary embolism...

[Drug-induced hypersensitivity syndrome in internal medicine: diagnostic and therapeutic traps. Eight observations].

Purpose: Drug-induced hypersensitivity syndrome (DIHS) is an acute and severe drug reaction. Manifestations include severe skin lesions, fever, nodal enlargement, blood eosinophilia and multisystemic involvement. The severe systemic manifestations of DIHS are responsible for a 10% mortality rate.

Role of drug exposure in aphthous ulcers: a case-control study.

Background: Drug-induced aphthous ulcers have been the subject of several isolated and heterogeneous case reports for the last three decades.

Objectives: To perform a case-control study to evaluate the risks linked to drug exposure in aphthous ulcers.

Methods: Eighty patients with typical clinical patterns of aphthous ulcers and 152 control patients who had had consultations for skin tumours were studied.

[Scurvy presenting with ecchymotic purpura and hemorrhagic ulcers of the lower limbs].

Introduction: The risk of vitamin C deficiency is underestimated in industrialized countries and is only disclosed in rare cases of severe scurvy.

Case Report: We report three cases of scurvy presenting with ecchymotic purpura and hemorrhagic ulcerations of the lower limbs. Vitamin C supplementation led to rapid improvement of the skin lesions.