Publications by authors named "P De Stefano"

Purpose: Recent research on quantitative EEG in coma has proposed several metrics correlating with consciousness level. However, the heterogeneous nature of coma can challenge the generalizability of these measures. This study investigates alpha-coma, an electroclinical pattern characterized by a widespread, nonreactive alpha rhythm often linked to poor outcomes.

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Objectives: Although myoclonus less than or equal to 72 hours after cardiac arrest (CA) is often viewed as a single entity, there is considerable heterogeneity in its clinical and electrophysiology characteristics, and its strength of association with outcome. We reviewed definitions, electroencephalogram, and outcome of myoclonus post-CA to assess the need for consensus and the potential role of electroencephalogram for further research.

Data Sources: PubMed, Embase, and Cochrane databases.

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Pectus excavatum (PE) can be associated with either congenital or acquired heart disease. This study highlights the importance of PE surgical repair in cases of severe chest depression on the heart in underlying cardiac diseases exacerbating cardiopulmonary impairment. From January 2023 to March 2024, four male patients underwent PE repair, having heart disease including pericarditis, mitral valve prolapse, ventricular fibrillation arrest and type 1 second-degree atrioventricular block.

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Background: Outcome prediction in Status epilepticus (SE) aids in clinical decision-making, yet existing scores have limitations due to SE heterogeneity. Serum albumin is emerging as a readily available prognostic biomarker in various clinical conditions. This study evaluates hypoalbuminemia in predicting short- and long-term mortality.

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Article Synopsis
  • Septic embolization, a common complication of infective endocarditis (IE), can lead to serious issues like acute coronary syndrome, although it's rare and affects 22-50% of patients.
  • This study analyzed 649 patients with left-sided IE from 2013 to 2023, focusing on coronary embolism (CE) through various diagnostic methods, with a median follow-up duration of 4.7 years.
  • Results showed CE occurred in only 1.2% of patients, primarily treated surgically, and those with CE were more likely to have cerebral embolisms, highlighting the need for early detection and better management strategies in IE cases.
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