Publications by authors named "P De Stefanis"
Article Synopsis
- The study investigates the potential benefits of IgM-enriched intravenous immunoglobulins (IGAM) for severe COVID-19 patients, focusing on those who are often admitted to intensive care during advanced stages when other treatments are less effective.
- Conducted at a university hospital in Italy, the research compares outcomes of 56 patients treated with Pentaglobin IGAM to a control group of 169 untreated patients from March 2020 to April 2021.
- Results indicate that IGAM-treated patients experienced shorter timeframes to hospitalization and better clinical markers (lower D-dimer and improved P/F ratio), suggesting that IGAM treatment may have protective effects against mortality.
Article Synopsis
- This study investigates how echocardiographic laboratories in Italy were organized and operated during the second wave of the COVID-19 pandemic, comparing it to the same period in 2019.
- Findings show significant reductions in both hospital and outpatient echocardiographic activities, with many labs partially or fully interrupted during the pandemic.
- Safety measures improved for operators, with a widespread use of personal protective equipment, and the study noted an increase in outpatient waiting times for echocardiograms and a rise in the use of point-of-care cardiac ultrasound during the pandemic.
Mid Regional pro-ADM (MR-proADM) is a promising novel biomarker in the evaluation of deteriorating patients and an emergent prognosis factor in patients with sepsis, septic shock and organ failure. It can be induced by bacteria, fungi or viruses. We hypothesized that the assessment of MR-proADM, with or without other inflammatory cytokines, as part of a clinical assessment of COVID-19 patients at hospital admission, may assist in identifying those likely to develop severe disease.
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