Publications by authors named "P De Boever"
Article Synopsis
- Long-term head-down bedrest (HDBR) simulates weightlessness and negatively impacts the retina and cerebrovascular regulation in healthy males.
- Participants experienced a decrease in retinal arteriolar diameter by day 8 and an increase in venular diameter by day 16, along with higher blood pressure and lower cerebral blood flow velocity during HDBR.
- An anti-inflammatory/antioxidant cocktail did not reverse these vascular changes, suggesting it was ineffective in restoring normal microcirculation and cerebral blood flow.
Background: Emerging evidence points to the beneficial role of greenspace exposure in promoting cardiovascular health. Most studies have evaluated such associations with conventional cardiovascular endpoints such as mortality, morbidity, or macrovascular markers. In comparison, the microvasculature, a crucial compartment of the vascular system where early subclinical signs of cardiovascular problems appear, has not been studied in association with greenspace exposure.
View Article and Find Full Text PDFObjectives: The effects of HIV and antiretroviral therapy (ART) on microvascular function are poorly explored. We compared retinal vessel functional responses to flicker light-induced provocation (FLIP) in people living with HIV (PLWH) and people living without HIV (PLWoutH).
Methods: We included 115 PLWH and 51 PLWoutH with a median age of 41 years.
Viral infection frequently affects the cardiovascular system, and vascular disturbances in patients can lead to health complications. One essential component of the cardiovascular system that is vulnerable to the inflammatory effects of viral infections is the microcirculatory system. As a suitable and practical non-invasive method to assess the structure and function of the retinal microcirculation, a proxy for the microcirculatory system, retinal fundus imaging can be used.
View Article and Find Full Text PDFCardiovascular risk is a health concern in people living with HIV/AIDS (PLWH). This longitudinal study (baseline vs 36 months) aimed to investigate the relationship between body composition and markers of cardiovascular risk in a South African study population [HIV free, = 22 vs HIV positive on antiretroviral therapy (HIV+ART), = 73)]. Health questionnaires, anthropometric measurements, biochemical analyses and flow-mediated dilation were performed.
View Article and Find Full Text PDF