Antiinflammatory and immunostimulant activities of six sulphur compounds--four benzenesulphonates, levamisole, and pyritinol hydrochloride--assayed in mouse cell activation studies.

The effect of a phlogogenic agent and of six sulphur compounds on peritoneal macrophages, spleen B lymphocytes, and von Kupffer cells of the liver has been observed in BALB/C mice. The phlogogenic agent (0.5% carrageenin + 10% peptone) was a potent stimulant of the macrophages (increasing their number, protein content, and acid phosphatase activity), the lymphocytes (increase of haemolytic plaque counts), and the von Kupffer cells (increase of the colloidal carbon clearance rate which measures phagocytic capacity).

[Present data on inflammation. III. Experimentally induced inflammation (author's transl)].

In a previous chapter, the importance of macrophages in inflammatory processes was emphasized upon. The authors now mention the outstanding inflammatory agents utilized for experimental purposes, especially as regards the pattern of their action. Finally, this paper restates the question of the pharmacology and therapy in inflammation.

[Present data about inflammation. I. Inflammatory process (author's transl)].

The authors reviewed the data about inflammatory diseases acquired in the last few years. They have studied clinical aspects of inflammatory reaction, the various mediators of inflammation and physiological anti-inflammatory molecules.