Publications by authors named "P Dastidar"

Article Synopsis
  • Researchers developed a self-drug-delivery system using a supramolecular gelator called NAP-PHE∙PEA, derived from naproxen and amino acids, capable of gelling both water and organic solvents.* -
  • The study explored the molecular interactions governing the gel's formation using techniques like 1H-NMR spectroscopy and X-ray diffraction to understand the gel-network structure and analyze various salt forms.* -
  • NAP-PHE∙PEA demonstrated strong anti-cancer effects on certain cancer cell lines without harming normal cells, and its gel form exhibited beneficial properties such as self-healing and load-bearing, making it suitable for topical treatments.*
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The prevalence of microplastics (MPs, <5 mm) in natural environments presents a formidable global environmental threat MPs can be found from the Arctic to Antarctica, including glaciers. Despite their widespread distribution, studies on MP accumulation in apex predators inhabiting Polar Regions remain limited. The objective of this study was to conduct a comprehensive examination, for the first time, of MP bioaccumulation in various organs and tissue of Adélie penguins.

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Supramolecular gels are an important class of materials that are promising for its wide range of applications including drug delivery. While supramolecular gels are intrinsically porous because of the 3D nano-matrix (gel matrix) that is being formed due to supramolecular self-assembly process involving the gelator molecules during gelation, additional nanopores can be introduced to the overall gel if the gelator molecule itself holds molecular cavity such as metal-organic-cage (MOC) molecules. A MOC having the molecular formula [(PdL2).

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To evaluate and compare the effect of calcium hydroxide [Ca(OH)] and 2-hydroxyisocaproic acid (HICA) on the microhardness of root dentine. Fifty-one matured maxillary central incisors with straight root and type I canal configuration were decoronated to a standardized length of 16 mm. The root canals were cleaned and shaped using rotary instruments up to size F5.

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A skin wound is prone to bacterial infection and growth. An antibacterial topical hydrogel that can act as a self-drug-delivery (SDD) system is reported here. Two bidentate ligands () derived from imidazole/benzimidazole derivatives when reacted with Zn(NO) and a series of nonsteroidal-anti-inflammatory drugs (NSAIDs) produced crystalline products, which were characterized by single-crystal X-ray diffraction (SXRD).

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