Publications by authors named "P Dambruoso"
Article Synopsis
- A study was conducted to evaluate preoperative platelet function in patients receiving antiplatelet drugs before coronary artery bypass grafting (CABG), aiming to shorten surgical wait times.* -
- The research involved 48 patients on various P2Y12 receptor blockers and assessed their platelet response using thromboelastography-platelet mapping, revealing resistance rates of 25% for clopidogrel, 33% for ticagrelor, and 33% for prasugrel.* -
- Findings suggested that identifying resistance to these medications can significantly reduce CABG waiting times compared to existing guidelines, thereby minimizing potential life-threatening delays.*
Astrocytes are responsible for maintaining homoeostasis and cognitive functions through calcium signalling, a process that is altered in brain diseases. Current bioelectronic tools are designed to study neurons and are not suitable for controlling calcium signals in astrocytes. Here, we show that electrical stimulation of astrocytes using electrodes coated with graphene oxide and reduced graphene oxide induces respectively a slow response to calcium, mediated by external calcium influx, and a sharp one, exclusively due to calcium release from intracellular stores.
View Article and Find Full Text PDFNovel polyhydroxylated ammonium, imidazolium, and pyridinium salt organocatalysts were prepared through N-alkylation sequences using glycidol as the key precursor. The most active pyridinium iodide catalyst effectively promoted the carbonation of a set of terminal epoxides (80 to >95% yields) at a low catalyst loading (5 mol%), ambient pressure of CO, and moderate temperature (75 °C) in batch operations, also demonstrating high recyclability and simple downstream separation from the reaction mixture. Moving from batch to segmented flow conditions with the operation of thermostated (75 °C) and pressurized (8.
View Article and Find Full Text PDFArticle Synopsis
- * Continuous measurements of Gaseous Elemental Mercury (GEM) were taken, examining factors like temperature and wind speed that affect local mercury emissions, alongside regional pollution sources such as mining and coal plants.
- * The study also looked at the impact of vegetation on GEM levels and investigated the potential effects of wildfires and vegetation dryness on mercury emissions during specific events.