Publications by authors named "P D Twigg"

A composite silicone skin adhesive material was designed to improve its water vapor permeability to offer advantages to wearer comfort compared to existing skin adhesive dressings available (including perforated silicone and hydrocolloid products). The chemical and mechanical properties of this novel dressing were analyzed to show that it has a high creep compliance, offering anisotropic elasticity that is likely to place less stress on the skin. A participant study was carried out in which 31 participants wore a novel silicone skin adhesive (Sil2) and a hydrocolloid competitor and were monitored for physiological response to the dressings.

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Flavonoids are potent antioxidants that play a role in defense against pathogens, UV-radiation, and the detoxification of reactive oxygen species. Dihydroflavonol 4-reductase (DFR) and flavanone 4-reductase (FNR) reduce dihydroflavonols and flavanones, respectively, using NAD(P)H to produce flavan-(3)-4-(di)ols in flavonoid biosynthesis. Anthocyanidin reductase (ANR) reduces anthocyanidins to flavan-3-ols.

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Yellow sugarcane aphid (YSA) (, Forbes) is a damaging pest on many grasses. Switchgrass ( L.), a perennial C4 grass, has been selected as a bioenergy feedstock because of its perceived resilience to abiotic and biotic stresses.

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Article Synopsis
  • Switchgrass is a key biofuel crop but is affected by greenbug infestation, which impacts protein expression and phosphorylation.
  • In a study, 3,594 proteins from switchgrass were analyzed, revealing 429 were differentially expressed due to GB infestation, with 291 proteins upregulated and 138 downregulated.
  • Phosphoproteome analysis identified 310 differentially phosphorylated proteins, showing a shift towards proteins associated with plant defense while repressing those linked to photosynthesis.
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Aphid herbivory elicits plant defense-related networks that are influenced by host genetics. Plants of the upland switchgrass ( ) cultivar Summer can be a suitable host for greenbug aphids (; GB), and yellow sugarcane aphids (, YSA), whereas the lowland cultivar Kanlow exhibited multi-species resistance that curtails aphid reproduction. However, stabilized hybrids of Summer (♀) x Kanlow (♂) (SxK) with improved agronomics can be damaged by both aphids.

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