Publications by authors named "P D Theocharis"

Article Synopsis
  • Menopausal hormone therapy (MHT) may increase the risk of skin cancers, specifically melanoma and keratinocyte cancer (KC), according to a systematic review and meta-analysis of existing studies.
  • The analysis included data from 27 studies involving over 2.6 million menopausal women, revealing a significant association between MHT and skin cancer risks, including increased hazard ratios for both melanoma and KC.
  • Longer use of MHT, particularly more than five years and current usage, was linked to a heightened risk, with estrogen monotherapy showing a particularly strong association.
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Multi-system inflammatory syndrome in children (MIS-C) causes widespread inflammation including a pancarditis in the weeks following a COVID infection. As we prepare for further coronavirus surges, understanding the medium-term cardiac impacts of this condition is important for allocating healthcare resources. A retrospective single-center study of 67 consecutive patients with MIS-C was performed evaluating echocardiographic and electrocardiographic (ECG) findings to determine the point of worst cardiac dysfunction during the admission, then at intervals of 6-8 weeks and 6-8 months.

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Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that can affect virtually any organ, including middle and/or inner ear. The objective of the current systematic review and meta-analysis was to investigate the association of SLE with the different subtypes of hearing loss. This systematic review and meta-analysis was conducted in agreement with the PRISMA guidelines.

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Objective: To analyze findings and trends on serial electrocardiograms (ECGs) in multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease taken during the course of illness and at follow-up.

Study Design: We included all children presenting with MIS-C at a single center with 3 or more ECGs taken during the course of their illness. We measured ECG intervals (PR, QRSd, and QTc) and amplitudes (R-, S-, and T-waves) on each ECG and documented any arrhythmias and ST-segment changes.

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