Publications by authors named "P D Makwana"

Staphylococcus pseudintermedius is considered as a most common cause of canine pyoderma. Antimicrobial resistance is considered as a global public health concern. The main aim of the study was to evaluate the distribution of Antimicrobial resistance genes in S.

View Article and Find Full Text PDF

Background: Follicle-stimulating hormone receptor () and luteinizing hormone/choriogonadotropin receptor () are integral to ovarian function, facilitating follicle development and maturation through their respective hormonal interactions. The influence of receptor polymorphisms on the outcomes of freeze-all cycles remains unclear.

Objective: This study investigates the impact of and polymorphisms on clinical outcomes in freeze-all cycles.

View Article and Find Full Text PDF
Article Synopsis
  • - The study highlights the importance of scaffold design in tissue engineering, specifically focusing on how different micropatterned substrates influence cell behavior, particularly pre-osteoblasts (MC3T3-E1 cells).
  • - Researchers fabricated grid-lined micropatterned PCL-Collagen nanofibers (GLMPCnfs) to observe their effects on cell alignment and differentiation compared to unpatterned controls (NPPCnfs), finding that GLMPCnfs led to greater cellular alignment and osteogenic activity.
  • - Results showed a significant reduction in the area of GLMPCnfs due to electrofocusing during fabrication, and aligned cells displayed increased alkaline phosphatase activity and upregulation of osteogenic markers
View Article and Find Full Text PDF

Despite of being in different microenvironment, breast cancer cells influence the bone cells and persuade cancer metastasis from breast to bone. Multiple co-culture approaches have been explored to study paracrine signaling between these cells and to study the progression of cancer. However, lack of native tissue microenvironment remains a major bottleneck in existing co-culture technologies.

View Article and Find Full Text PDF

Scaffolds for bone tissue engineering require considerable mechanical strength to repair damaged bone defects. In this study, we designed and developed mechanically competent composite shape memory triphasic bone scaffolds using fused filament fabrication (FFF) three dimensional (3D) printing. Wollastonite particles (WP) were incorporated into the poly lactic acid (PLA)/polycaprolactone (PCL) matrix as a reinforcing agent (up to 40 wt%) to harness osteoconductive and load-bearing properties from the 3D printed scaffolds.

View Article and Find Full Text PDF