Publications by authors named "P D Leeson"

Background: Preterm birth (< 37 weeks' gestation) alters cerebrovascular development due to the premature transition from a foetal to postnatal circulatory system, with potential implications for future cerebrovascular health. This study aims to explore potential differences in the Circle of Willis (CoW), a key arterial ring that perfuses the brain, of healthy adults born preterm.

Methods: A total of 255 participants (108 preterm, 147 full-term) were included in the analysis.

View Article and Find Full Text PDF
Article Synopsis
  • The COVID-19 pandemic increased the reliance on telemedicine, particularly in maternity care, leading to the BUMP trials which evaluated self-monitoring blood pressure for pregnant individuals at risk of hypertension.
  • Qualitative interviews with 39 pregnant women revealed that while self-monitoring was generally seen as reassuring and empowering, it also created uncertainty and added responsibility, causing some women to opt out of the intervention.
  • Ultimately, the BUMP trials did not demonstrate significant improvements in early detection or management of hypertension from blood pressure self-monitoring in pregnant women at higher risk for preeclampsia.
View Article and Find Full Text PDF

Aims: Stress echocardiography is widely used to assess patients with chest pain. The clinical value of a positive or negative test result to inform on likely longer-term outcomes when applied in real-world practice across a healthcare system has not been previously reported.

Methods And Results: Five thousand five hundred and three patients recruited across 32 UK NHS hospitals between 2018 and 2022, participating in the EVAREST/BSE-NSTEP prospective cohort study, with data on medical outcomes up to 2023 available from NHS England were included in the analysis.

View Article and Find Full Text PDF