Publications by authors named "P D Laforgia"
Objectives: This study aimed to detail the technical management of Medina 0.0.1 lesions, assess their outcomes, and identify predictors of Major Adverse Cardiovascular Events (MACE).
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- Intracoronary continuous thermodilution is a new method to measure coronary flow and microvascular resistance, but its effectiveness in patients with angina and non-obstructive coronary arteries (ANOCA) is still unclear.
- This study involved 120 patients undergoing coronary function tests, including acetylcholine testing, to assess their coronary flow and microvascular function.
- Results showed that a high percentage of patients had positive coronary function tests, and specific measurements (Qmax and Rμ,hyper) were linked to these positive results, suggesting that the continuous thermodilution technique could help understand different ANOCA profiles better.
Three-year clinical outcomes after transcatheter aortic valve implantation in patients with bicuspid aortic disease: Comparison between self-expanding and balloon-expandable valves.
Mauro Boiago Michele Bellamoli Chiara De Biase Alessandro Beneduce Lola Gutierrez Alonso Pietro Laforgia
Catheter Cardiovasc Interv
May 2024
Article Synopsis
- Bicuspid aortic valve (BAV) stenosis poses challenges for transcatheter aortic valve implantation (TAVI), with positive short-term results but limited long-term data available.
- A study analyzed 150 patients who underwent TAVI comparing self-expanding valves (SEV) and balloon-expandable valves (BEV), looking at outcomes like mortality, stroke, and the need for valve reintervention over three years.
- Results showed no significant differences in primary or secondary outcomes between SEV and BEV groups, indicating similar long-term clinical effectiveness for both valve types in BAV patients.
Article Synopsis
- The study assesses the effectiveness of self-expanding (SE) Evolut PRO/PRO+ versus balloon-expandable (BE) SAPIEN ULTRA valves in patients with small aortic annuli, using data from the OPERA-TAVI registry.
- It finds that the 1-year primary effectiveness outcomes are similar for both valve types, but the SE group shows better results for 30-day device-related outcomes.
- The SE valves have higher rates of disabling strokes and paravalvular leaks, while the BE valves exhibit more issues with prosthesis-patient mismatch and elevated residual mean gradients.