Publications by authors named "P D Kothari"
Background: Chemokines, along with their receptors, exert critical roles in tumor development and progression. In prostate cancer (PCa), interleukin-8 (IL-8/CXCL8) was shown to enhance angiogenesis, proliferation, and metastasis. CXCL8 activates two receptors, CXCR1 and CXCR2.
View Article and Find Full Text PDFVaricocele has been associated with reduced male fertility potential. Treatment modalities for varicocele improve semen parameters, yet more than 50% of cases remain infertile. Varicocele-induced heat and hypoxia stress may affect sperm mitochondrial functions, possibly leading to aberrant epigenetic modifications.
View Article and Find Full Text PDFArticle Synopsis
- Breast vascularity is vital for understanding breast cancer development and treatment, as it provides insights into pathological and physiological changes in breast tissue.
- * Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a key tool for assessing breast vascularity, using contrast agents to visualize blood flow and differentiate between benign and malignant lesions.
- *DCE-MRI offers high diagnostic accuracy and is useful for monitoring treatment response, but challenges like cost and overlapping enhancement patterns need to be addressed, alongside future advancements in imaging technology.*
Aim: To evaluate and compare the clinical and radiographic success of NeoPUTTY® and Biodentine™ as indirect pulp treatment (IPT) materials in primary molars.
Materials And Methods: This clinical trial was conducted on children aged 5-9 years. Class I carious lesions in primary molars indicated for IPT were divided into two groups-group I, NeoPUTTY®, and group II, Biodentine™.