Publications by authors named "P D Keefe"
In this review, we provide an evidence-based approach to determine the cellular and systemic actions of two structurally similar flavonoids, apigenin and chrysin. We have clearly evaluated and charted the overlapping and diverging properties of these two sister flavonoids. Based on two separate Omics-based approaches by our group and independent reports from others, the cholesterol-lowering properties have been revealed.
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- An 18-year-old boy had severe stomach pain and was found to have air in his belly, which can mean something is wrong inside.
- Doctors figured out that he had a problem called perforated Meckel's diverticulum, where a part of his intestine got infected and caused a hole.
- After some tests and surgery to remove the damaged part of his intestine, the doctors confirmed the issue and showed that doctors need to think about Meckel's diverticulum when young people have these kinds of belly problems.
Polyglutamine diseases comprise a cluster of genetic disorders involving neurodegeneration and movement disabilities. In polyglutamine diseases, the target proteins become aberrated due to polyglutamine repeat formation. These aberrant proteins form the root cause of associated complications.
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