Publications by authors named "P D Danielson"

Biological fluids are proteinaceous liquids or suspensions released through different body orifices or through penetration of the skin. These fluids are the result of multiple tissues and cell types and contain extensive, highly complex, and dynamic protein populations that reflect both the transcriptional program of the originating cells and a record of the individual's health status. Body fluids are readily accessible to clinicians and researchers, and as such proteomic analyses are an important component of clinical studies, fertility studies, oral health studies, and forensic investigations.

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Article Synopsis
  • Keratocytes are vital cells in the corneal stroma, influencing corneal health and healing, and understanding their response to strain can enhance treatment for corneal injuries.
  • In the study, applying 3% strain to human keratocytes increased the protein ALDH3A1, which in turn inhibited the NF-κB signaling pathway, reducing cell proliferation and migration.
  • Experiments using mouse models and patients with keratoconus indicated that higher corneal strain correlates with elevated ALDH3A1 levels, providing insights into the mechanisms behind corneal injury and repair.
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The annual meeting for the Intermountain Branch was held in April 2024 on the campus of Brigham Young University. There were 127 branch members from Utah, Idaho, and Nevada who attended the meeting and were composed of undergraduate students, graduate or medical students, and faculty. This report highlights the diversity of, and the emerging trends in, the research conducted by American Society for Microbiology members in the Intermountain Branch.

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This case report describes a 17-year-old patient with a low-grade appendiceal mucinous neoplasm. The patient presented with non-bloody diarrhea, abdominal pain, and weight loss. A colonoscopy revealed a cecal polypoid mass that required laparoscopic surgery.

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The enzyme α-amylase has long been a commonly targeted protein in serological tests for saliva. While being especially abundant in saliva, α-amylase is detectable in vaginal secretions, sweat, fecal matter, breast milk and other matrices. As a result, assays for α-amylase only provide a presumptive indication of saliva.

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