Publications by authors named "P D Agrba"
Article Synopsis
- Modern optical bioimaging trends seek innovative nanoproducts that offer both high image contrast and effective treatment capabilities.
- Silicon nanoparticles, created through picosecond laser ablation of porous silicon films and nanowire arrays in water and ethanol, show promise as contrasting agents for imaging techniques like fluorescence and optical coherence tomography.
- These nanoparticles, measuring under 100 nm and exhibiting crystalline phases, demonstrate effective fluorescence and light scattering, paving the way for their application in biophotonics, as evidenced by preliminary optical imaging experiments.
Background/purpose: The goal of the study is comparative analysis of the layers in OCT images and the morphological structure of skin with thick and thin epidermis.
Methods: We analyzed the difference between skin with thin and thick epidermis in two ways. The first approach consisted in determination of the thicknesses of layers of skin with thin and thick epidermis of different localizations from experimental OCT images.
Background/purpose: The present study aimed to investigate the influence of topical corticosteroid therapy and tacrolimus on morphological indices of different skin phototypes and to optimize topical therapy using the OCT technique.
Methods: Twenty healthy volunteers aging from 20 to 30 (14 men and 6 women) took part in the study: 10 persons with skin phototype I, II and 10 persons with skin phototype V, VI. Morphological state of the skin was assessed before and during application of topical steroids of different strength and calciumneurin inhibitors for 49 days.
Objective: The goal of the described study was complex assessment of age-specific morphofunctional features of skin of different anatomic localization using optical coherence tomography (OCT).
Methods: Forty-three healthy volunteers aging from 4 to 74 years were enrolled in the study. Optical and functional skin parameters were studied in 18 areas of the human body.
Modern optical diagnostic techniques often require deformations of the studied bio-tissues for image acquisition. This paper discusses the effect of mechanical compression on the formation of OCT images of human skin. The study was performed in vivo on human volunteers of different age.
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