Publications by authors named "P Custodio"
Article Synopsis
- The study investigates long-term health outcomes of young patients (60 and under) with coronary artery disease, comparing two treatment strategies: CABG (coronary artery bypass grafting) and PCI (percutaneous coronary intervention).
- Results indicate that CABG is associated with lower all-cause death rates and fewer new revascularizations and hospital readmissions over a median follow-up of 9.3 years, although it had a higher risk of death/stroke in the first 30 days post-procedure.
- The findings suggest that for young patients with low-complexity coronary anatomy, CABG may offer better long-term health outcomes compared to PCI, despite an initial increase in short-term risks.
One of the most common techniques found in a cell biology or tissue engineering lab is the cytotoxicity assay. This can be performed using a variety of different dyes and stains and various protocols to result in a clear indication of dead and live cells within a culture to quantify the viability of a culture and monitor for sudden drops or increases in viability by a drug, material, viral vector, etc introduced into the culture. This assay helps cell biologists determine the health of their culture and what toxicity added substances may add to the culture and whether they are appropriate and safe to use with human cells.
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- The study investigates mitral annulus disjunction (MAD) using cardiac MRI in a group of 222 patients with an average age of 49.2 years, primarily male (56.8%).
- MAD is identified by a separation of 2 mm or more between the left ventricular myocardium and the mitral annulus, and the study analyzes late gadolinium enhancement (LGE) patterns and ventricular arrhythmias (VA).
- Results show that although non-sustained ventricular arrhythmias were more common in patients with greater MAD extent, no strong relationship between LGE and MAD severity was found, with no observed sustained VAs during the follow-up period of approximately 4 years.
Introduction And Objectives: Oral anticoagulation (OAC) with non-vitamin K antagonist oral anticoagulants (NOACs) after surgical mitral valve repair (MVR) or bioprosthetic valve replacement (BVR) in mitral position remains a controversial topic among the cardiovascular community, in particular in the early postoperative period. This study aimed to evaluate the efficacy and safety of NOACs in the first three months after MVR or mitral BVR compared to vitamin K antagonists (VKAs).
Methods: This was a single-center retrospective study with prospectively collected peri-intervention outcomes between 2020 and 2021.
Background: Atrioventricular conduction abnormalities due to acute myocarditis are typically transient and do not require ventricular pacing beyond the acute phase of myocardial inflammation. Notwithstanding, selective injury and necrosis of the heart's conduction system may lead to persistent complete heart block (CHB) requiring device implantation.
Case Summary: We report the case of a 23-year-old man with acute lymphocytic myocarditis complicated by cardiogenic shock, cardiac arrest due to ventricular fibrillation, and persistent CHB.