Publications by authors named "P Crupi"

Background: Mediterranean diet may enhance cognitive function and delay the progression of Alzheimer's disease (AD). We conducted a systematic review to investigate the effect of oleocanthal (OC) from extra-virgin olive oil (EVOO) on amyloid-β (Aβ) burden in preclinical models of AD, considering the anti-inflammatory and neuroprotective effects of EVOO biophenols, which are key components of the Mediterranean dietary model.

Methods: The literature was searched through six electronic databases until February 2023.

View Article and Find Full Text PDF
Article Synopsis
  • - Waste from the agri-food chain, specifically olive oil wastewater, can be transformed into a valuable supplement enriched with hydroxytyrosol (HT), which might help prevent cardiovascular diseases.
  • - Although it doesn't significantly change heart and blood vessel functions in "ex vivo" studies, it effectively removes harmful reactive oxygen species and reduces inflammatory markers in "in vitro" tests.
  • - The extract also shows potential for lowering arterial stiffness, which could lead to reduced blood pressure and improved heart function, suggesting its dual role in cardiovascular health and infection prevention.
View Article and Find Full Text PDF

Polyphenols are secondary metabolites found in plants, foods, and drinks, occurring in small quantities and showcasing antioxidant and anti-inflammatory qualities. The primary polyphenols consist of flavonoids, phenolic acids, stilbenes, and lignans. However, there is currently no comprehensive quantitative analysis of epidemiological data on overall death rates.

View Article and Find Full Text PDF

Table olives are one of the most known fruit consumed as fermented food, being a fundamental component of the Mediterranean diet. Their production and consumption continue to increase globally and represent an important economic source for the producing countries. One of the most stimulating challenges for the future is the modernization of olive fermentation process.

View Article and Find Full Text PDF

In 2011, the European Food Safety Authority (EFSA) accorded a health claim to olive oil polyphenols in that they protected LDL particles from oxidative damage. However, limited scientific evidence has so far failed to confer any claim of function on the maintenance of normal lipid metabolism. We performed a systematic review and meta-analysis of human RCTs, evaluating the effect of olive oil polyphenol administration on lipid profiles.

View Article and Find Full Text PDF