Effect of vitamin C on ambulatory blood pressure and plasma lipids in older persons.

Objectives: To determine the effect of oral vitamin C supplements on ambulatory blood pressure and plasma lipids.

Design: A 6-month double-blind randomized placebo-controlled cross-over study with a 1 -week washout between cross-over periods.

Methods: Vitamin C 500 mg daily or matching placebo was given to 40 men and women aged between 60 and 80 years for 3 months each in a cross-over fashion.