Publications by authors named "P Cramon"
Abnormal uptake related to the thyroid gland on somatostatin receptor-targeted PET imaging: reported prevalence and rate of thyroid malignancy and parathyroid adenomas.
Endocr Connect
December 2024
Article Synopsis
- Incidental uptake of tracers in or near the thyroid gland was found in a small percentage of patients undergoing specific PET scans for neuroendocrine neoplasms (NENs), raising questions about its significance.
- Out of 1808 patients, 42 showed abnormal thyroid uptake, with 5 diagnosed with thyroid malignancies and 13 suggesting possible parathyroid adenomas.
- The findings indicate a low overall prevalence but notable rates of malignancy and parathyroid conditions, highlighting the need for further studies to establish the best approaches for managing these incidental findings.
Purpose: Preoperative iodine therapy in toxic nodular goiter (TNG) is discouraged as iodine may cause aggravation of hyperthyroidism. We aimed to examine if a short course of iodine treatment is safe to administer in TNG.
Methods: Patients with TNG (n=20) and subclinical to mild hyperthyroidism (free (f)T4 <30 pmol/L) without complicating illnesses were included in this pre-post-intervention study at Karolinska University Hospital.
Primary hyperparathyroidism (PHPT) is the most prevalent cause of hypercalcaemia, affecting 0.3% of the population. The only curative procedure is parathyroidectomy.
View Article and Find Full Text PDFArticle Synopsis
- Researchers wanted to see if taking selenium would help improve the quality of life for people with autoimmune thyroiditis.
- They studied 412 patients over 12 months by giving some of them selenium and others a placebo (fake pill), but found that both groups felt similarly about their quality of life after a year.
- Even though selenium lowered certain antibody levels in the blood, it didn't change how much medication the patients needed or make them feel any better than those who didn’t take it.
Attenuation Correction of Long Axial Field-of-View Positron Emission Tomography Using Synthetic Computed Tomography Derived from the Emission Data: Application to Low-Count Studies and Multiple Tracers.
Diagnostics (Basel)
December 2023
Recent advancements in PET/CT, including the emergence of long axial field-of-view (LAFOV) PET/CT scanners, have increased PET sensitivity substantially. Consequently, there has been a significant reduction in the required tracer activity, shifting the primary source of patient radiation dose exposure to the attenuation correction (AC) CT scan during PET imaging. This study proposes a parameter-transferred conditional generative adversarial network (PT-cGAN) architecture to generate synthetic CT (sCT) images from non-attenuation corrected (NAC) PET images, with separate networks for [F]FDG and [O]HO tracers.
View Article and Find Full Text PDF