Publications by authors named "P Costenaro"

Article Synopsis
  • The incidence of pediatric inflammatory bowel disease (IBD), such as Crohn's disease, is rising, and treatments like tumor necrosis factor alpha inhibitors have improved patient outcomes, though some patients don't respond to these therapies.!
  • A case study reported on a 12-year-old girl with Crohn's disease who developed a disseminated mycobacterial infection presenting as reactive polyarthritis while on various immunosuppressants, including ustekinumab.!
  • The findings suggest that children with IBD on immunosuppressive treatments are at an increased risk for mycobacterial infections, highlighting the need for careful monitoring and multiple specimen collection for diagnosis when symptoms arise.!
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Introduction: COVID-19 features changed with the Omicron variant of SARS-CoV-2 in adults. This study aims to describe COVID-19 symptoms in children and adolescents during the Parental, Delta, and Omicron eras.

Methods: A single-centre, prospective observational study was conducted on individuals aged 0-20 years attending the University Hospital of Padua (Italy) from April 2020 to December 2022.

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SARS-CoV-2 infection may impair behavior and mental health; we explored the psychological impact on parents and children who experienced COVID-19 within their families. A cross-sectional web-based survey was conducted on families attending the COVID-19 Follow-up Clinic at the Department for Women’s and Children’s Health, Padua (Italy). From April 2020 to August 2021, 75 surveys were collected from 66 families (97 parents and 129 children); almost 70% of participants had COVID-19, mostly asymptomatic/mildly symptomatic, and the median time from infection to survey compilation was 164.

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Importance: Understanding the long-term immune response against SARS-CoV-2 infection in children is crucial to optimize vaccination strategies. Although it is known that SARS-CoV-2 antibodies may persist in adults 12 months after infection, data are limited in the pediatric population.

Objective: To examine long-term anti-SARS-CoV-2 spike receptor-binding domain (S-RBD) IgG kinetics in children after SARS-CoV-2 infection.

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With a considerable morbidity and mortality burden, infective endocarditis still represents a challenge for clinicians. This is a case of persistent endocarditis in an extremely preterm newborn. The infection, initially treated with vancomycin, was successfully cured with daptomycin.

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