Publications by authors named "P Coste-Mazeau"
Background: Maternal agonistic autoantibodies against the angiotensin II type 1 receptor (AT1-AAs) have been implicated in the pathophysiology of preeclampsia, but their presence in their offsprings and their possible neonatal effects have not been specifically explored. This prospective study aimed to evaluate the presence of AT1-AAs and their potential clinical effects in neonates of AT1-AAs positive mothers.
Methods: Women with preeclampsia and their neonates were included.
Article Synopsis
- The study investigates the mechanical strength of fetal membranes in women at risk for preterm premature rupture of membranes (PPROM) through a series of tensile tests on tissue samples collected from pregnant women undergoing cesarean sections.
- Results indicate that first-time mothers (primiparous) have weaker fetal membranes compared to those with previous births, while factors like gestational diabetes and geographic origin affect membrane properties such as thickness and mechanical strength.
- Overall, thicker membranes show decreased rigidity and resistance, highlighting the complex interplay between various risk factors and membrane integrity in pregnancy.
Article Synopsis
- - Labor induction in France often involves using intravaginal dinoprostone (Propess®), but there's debate on whether to repeat this or switch to oxytocin if labor doesn’t start within 24 hours.
- - The study aimed to compare the effectiveness of a second Propess® placement followed by oxytocin versus direct oxytocin in increasing vaginal delivery rates among pregnant women who didn’t respond to the first Propess®.
- - Results showed no significant difference in vaginal delivery rates between the two methods (76.3% for the second Propess® vs. 73.8% for oxytocin), but more cesarean sections occurred in the Propess® group due to dilation issues.
Delivery before 25 weeks of gestation has become a more frequent occurrence in our maternity units and can be a difficult obstetrical situation to manage when the fetus is breech. We describe a new obstetrical maneuver enabling vaginal birth of a breech fetus before 25 weeks of gestation. It enables the fetal mobile to be fully grasped and secured, thus facilitating passage through the genital tract.
View Article and Find Full Text PDFAnalysis of the obstetrician's posture and movements during a simulated forceps delivery.
BMC Pregnancy Childbirth
April 2024
Background: The objective of this study was to identify and qualify, by means of a three-dimensional kinematic analysis, the postures and movements of obstetricians during a simulated forceps birth, and then to study the association of the obstetricians' experience with the technique adopted.
Method: Fifty-seven volunteer obstetricians, 20 from the Limoges and 37 from the Poitiers University hospitals, were included in this multi-centric study. They were classified into 3 groups: beginners, intermediates, and experts, beginners having performed fewer than 10 forceps deliveries in real conditions, intermediates between 10 and 100, and experts more than 100.