Publications by authors named "P Coquerelle"
Article Synopsis
- The study evaluated the retention rates, safety, and predictive factors for the use of subcutaneous TNF inhibitors (TNFi) in patients with axial spondyloarthritis (axSpA) based on real-life data from 552 patients.
- Results indicated that golimumab (GOL) had a significantly higher retention rate compared to adalimumab (ADA), etanercept (ETN), and certolizumab pegol (CZP), especially when prescribed as the first treatment option.
- Predictive factors for treatment cessation included female sex, peripheral disease, and the line of treatment, with primary inefficiency being the most common reason for stopping treatment.
Joint Bone Spine
March 2024
Article Synopsis
- Septic bursitis (SB) is a prevalent inflammatory condition, particularly linked to certain professions, and currently lacks standardized management guidelines.
- A collaborative group of healthcare specialists developed specific recommendations for treating olecranon and prepatellar SB, using a combination of literature review and expert insights.
- The newly established guidelines, aimed at various healthcare providers, emphasize the role of biological tests, imaging, antibiotic treatments, and address surgical options and prevention strategies.
Front Med (Lausanne)
October 2022
Article Synopsis
- Previous studies showed that biosimilars (bsDMARDs) and original treatments (boDMARDs) are similarly effective and safe, but less is known about their performance in naïve patients starting treatment for the first time.
- This study aimed to compare the treatment retention rates of bsDMARDs and boDMARDs across different diseases (like RA, SpA, and PsA) and specific molecules (etanercept and adalimumab), while also identifying predictive factors influencing treatment retention.
- Results indicated that bsDMARDs had a longer retention rate than boDMARDs (39 months vs. 23 months), particularly for etanercept in rheumatoid arthritis patients, and treatments containing citrate showed even better retention.*
Article Synopsis
- The study aims to evaluate how native joint septic arthritis (NJSA) is managed and the outcomes for patients in various rheumatology departments across France, covering cases from 2016 to 2017.
- A total of 362 NJSA patients were analyzed, revealing that knee involvement is common and that Staphylococcus aureus is the leading pathogen; treatment varied and included prolonged antibiotic use, surgeries, and challenges related to complications and mortality.
- The findings underscore a grim prognosis for NJSA, with significant morbidity and mortality rates, emphasizing the necessity for standardized management practices as outlined in new French guidelines released post-study.
