Publications by authors named "P Comby"

Objective: Many patients with ruptured intracranial aneurysms (RIAs) underrepresented or excluded from previous randomized controlled trials (RCTs) comparing surgery with endovascular treatment (EVT) are still considered for surgical clipping, but the best management of these patients remains unknown.

Methods: The International Subarachnoid Aneurysm Trial-2 was a randomized trial comparing surgical versus EVT of RIAs considered for surgical clipping, despite the results of previous RCTs, and also eligible for EVT. The primary endpoint was death or dependency according to the modified Rankin Scale score (mRS score > 2) at 1 year.

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Purpose: Various angiographic assessment scales have been used to report the results of endovascular treatment with the WEB device. We aimed to review the use and reliability of these scales.

Methods: We systematically reviewed studies reporting angiographic outcomes of WEB-treated aneurysms from January 2010 to May 2023.

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Background And Purpose: To evaluate the spectral scanner (Aquilion One PRISM Edition, Canon Medical Systems Corporation, Otawara, Japan) diagnostic performance to identify bone marrow edema (BME) in vertebrae of patients managed for suspected vertebral compression fracture in the emergency department of Dijon University Hospital.

Methods: 14 consecutive patients underwent spectral imaging and MRI spinal imaging, from January 2023 to March 2024 were retrospectively analyzed. 85 vertebrae were assessed for the detection of fracture on conventional CT images and the presence of bone marrow edema (BME) in all vertebral bodies on VNCa mapping for both Bone and Research preset, who was judged to indicate a fresh fracture.

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Objective: This study aimed to determine the predictive factors for analgesic reduction and amelioration of mobility following percutaneous sacroplasty in patients with insufficiency fractures or metastatic lesions.

Methods: A single-center retrospective analysis of 49 patients who underwent percutaneous sacroplasty for insufficiency fractures and sacral pathological lesions was conducted. Visual analog scale (VAS), Functional Mobility Scale (FMS), and Oswestry Disability Index (ODI) were assessed.

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Article Synopsis
  • The study aimed to track the outcomes of patients with brain arteriovenous malformations (AVMs) who were managed conservatively, revealing key statistics on related morbidity and mortality over a 10-year period.
  • Out of 1010 patients initially recruited, 434 were analyzed, with a majority having unruptured low-grade AVMs, demonstrating a 5% occurrence of serious outcomes and a higher risk in those with a history of rupture or older age.
  • During the follow-up of approximately 3.2 years, 8% of patients experienced major intracranial hemorrhages, highlighting the ongoing risks associated with conservative management of AVMs.
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