Publications by authors named "P Cocco"
Background: Machine learning has emerged as a potent tool in healthcare. A decision tree model was built to improve the decision-making process when determining the optimal choice between an open or robotic surgical approach for kidney transplant.
Methods: 822 patients (OKT) and 169 (RKT) underwent kidney transplantation at our centre during the study period.
Unlabelled: Target product profiles (TPPs) specify the essential properties tests must have to be able to address an unmet clinical need. To explore how early economic modeling can help to define TPP specifications based on cost-effectiveness considerations using the example of a new rapid diagnostic for infection (CDI), a contagious health care-associated infection causing potentially fatal diarrhea. A resource-constrained simulation model was developed to compare a hypothetical test for CDI with current practice (i.
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- Previous studies have shown that some human populations mixed with extinct species, influencing their ability to adapt to different environmental challenges through a process known as adaptive introgression.
- A key example involves a gene that helps Himalayan highlanders resist chronic mountain sickness, which was passed down from Denisovans through this gene flow.
- This research used advanced genetic analysis methods to identify multiple genes that have contributed to specific adaptations in Tibetan and Sherpa populations, particularly in their capacity to manage low oxygen levels at high altitudes.
Background: Whether hours on shift might impact adaptation to night shift work is still controversial.
Methods: We conducted a pooled analysis of two studies, including 170 hospital nurses working night shifts, 116 from a United Kingdom study working 12-hour rotating shifts, and 54 from Italy working 8-hour shifts. Both studies used the Epworth Sleepiness Scale (ESS) to detect sleepiness during routine daytime activities as an indicator of fatigue.
Background: Robotic-assisted kidney transplant (RAKT) has proven to be a successful approach for patients with morbid obesity and more centers are encouraged to apply robotic approach also for deceased donor kidney transplantation. Prolonged cold ischemia time (CIT) is accompanied by delayed graft function (DGF) and early graft loss after traditional open kidney transplant (OKT). This study examines the impact of CIT after robotic kidney transplantation on settings of deceased donation.
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