Oxygen Effect on 0-30 eV Electron Damage to DNA Under Different Hydration Levels: Base and Clustered Lesions, Strand Breaks and Crosslinks.

Studies on radiosensitization of biological damage by O began about a century ago and it remains one of the most significant subjects in radiobiology. It has been related to increased production of oxygen radicals and other reactive metabolites, but only recently to the action of the numerous low-energy electrons (LEEs: 0-30 eV) produced by ionizing radiation. We provide the first complete set of G-values (yields of specific products per energy deposited) for all conformational damages induced to plasmid DNA by LEEs (G (O)) and 1.

Comparisons between the Direct and Indirect Effect of 1.5 keV X-rays and 0-30 eV Electrons on DNA: Base Lesions, Stand Breaks, Cross-Links, and Cluster Damages.

The interaction of low energy electrons (LEEs; 1-30 eV) with genomic material can induce multiple types of damage that may cause the loss of genetic information, mutations, genome instability, and cell death. For all damages measurable by electrophoresis, we provide the first complete set of -values (yield of a specific product per energy deposited) induced in plasmid DNA by the direct and indirect effects of LEEs () and 1.5 keV X-rays () under identical conditions.

Pediatric emergency mental health presentations during early COVID-19: Comparing virtual and in-person presentations.

Increased mental health (MH) needs during the COVID-19 pandemic led to the implementation of a novel pediatric Emergency Department Virtual Care (EDVC) service. Our study aimed to describe the pediatric MH patient population that used EDVC by comparing patient-specific factors of those who obtained services virtually to those seen in-person. This retrospective chart review was conducted at a pediatric hospital in Eastern Ontario.

Physician Follow-Up of Pediatric and Young Adult Emergency Department Visits for Substance Use in Ontario, Canada.

Purpose: To study the proportion and predictors of outpatient physician follow-up within 60 days of substance-related emergency department (ED) visits for Ontario youth.

Methods: We examined administrative data on substance-related ED visits before and during the COVID-19 pandemic among youths aged 10-24 years in Ontario, Canada. Substance-related visits were identified using International Classification of Diseases-10-CA codes.

Binding energies of CD4 and fragment species to Pt(111): Implications for measurements of anion electron stimulated desorption.

We consider the electron stimulated desorption, via dissociative electron attachment, of anionic species from thin condensed CD4 films deposited on a Pt substrate and compare experimentally observed desorption yields with density functional theory calculations of the binding energies of various anionic and neutral moieties to Pt(111). Certain species (which can be considered chemisorbed) exhibit very high binding energies and large charge transfer with the substrate. Other "physisorbed" species have much lower binding energies.