Publications by authors named "P Chiesa"
Background: Smartphones and wearables are revolutionizing the assessment of cognitive and motor function in neurological disorders, allowing for objective, frequent, and remote data collection. However, these assessments typically provide a plethora of sensor-derived measures (SDMs), and selecting the most suitable measure for a given context of use is a challenging, often overlooked problem.
Objective: This analysis aims to develop and apply an SDM selection framework, including automated data quality checks and the evaluation of statistical properties, to identify robust SDMs that describe the cognitive and motor function of people with multiple sclerosis (MS).
Background: The Konectom™ smartphone-based cognitive processing speed (CPS) test is designed to assess processing speed and account for impact of visuomotor function on performance.
Objective: Evaluate reliability and validity of Konectom CPS Test, performed in clinic and remotely.
Methods: Data were collected from people with multiple sclerosis (PwMS) aged 18-64 years and healthy control participants (HC) matched for age, sex, and education.
The 2024 Interamerican Society of Cardiology (SIAC) guidelines on cardiorespiratory rehabilitation (CRR) in pediatric patients with congenital heart disease aim to gather and evaluate all relevant evidence available on the topic to unify criteria and promote the implementation of CRR programs in this population in Latin America and other parts of the world. Currently, there is no unified CRR model for the pediatric population. Consequently, our goal was to create these CRR guidelines adapted to the characteristics of congenital heart disease and the physiology of this population, as well as to the realities of Latin America.
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- Resting-state EEG alpha rhythms are typically strong in healthy adults but show abnormalities in individuals with subjective memory complaints (SMC) related to Alzheimer's disease amyloidosis.
- An exploratory study with 161 SMC participants assessed how these alpha rhythms relate to brain connectivity, specifically between the thalamus and visual cortex, while considering factors like amyloid burden and educational attainment (cognitive reserve).
- Findings indicated that SMC participants with low amyloid levels and higher education showed a positive link between EEG rhythms and brain connectivity, suggesting that cognitive reserve may mitigate the early effects of Alzheimer's on brain function.