Publications by authors named "P Chenlo"

Article Synopsis
  • - The study aimed to assess how the COVID-19 pandemic affected sperm quality in men, due to the presence of the virus's receptor in the testicles and the increased social isolation during the pandemic.
  • - Researchers analyzed 409 semen samples from men over two periods: before the pandemic and after. They found that men who had COVID-19 showed a significant decrease in sperm count, particularly in the acute phase, but levels returned to normal over time.
  • - The findings suggest that the reduction in sperm count is likely linked to temporary factors such as fever and inflammation rather than direct effects of the virus or the consequences of social isolation or vaccination.
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Background: Severe acute respiratory syndrome coronavirus 2, the virus responsible for coronavirus disease 2019, affects multiple organs. The virus enters cells through angiotensin-converting enzyme-2 and host factors present in genital organs, leading to concern over virus shedding in semen and reproductive function.

Objectives: To investigate severe acute respiratory syndrome coronavirus 2 in semen from patients with a mild infection, identify the seminal infected cells, and explore the effect of the infection on sex hormones and semen parameters.

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According to the Argentinian Ministry of Health records the number of patients requesting vasectomy increased twelve times in public hospitals in 2015-2019. The physicians and specialists account for this change in recent years, arguing, among other reasons, cultural change when male assumes active position in contraceptive methods. The article addresses vasectomized patient trajectory at the Buenos Aires University Clinical Hospital "José de San Martín".

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Objectives: The aim of this study was to establish analytical quality specifications for human semen measurands according to the state of the current methodologies.

Methods: Measurement errors were estimated based on data from participating laboratories in the External Quality Program (PEEC) led by the Argentine Biochemistry Foundation using the "Analytical Quality Minimum Specifications" model established in Spain for other biochemical collection parameters. Semen samples from the PEEC were analyzed according to WHO procedures.

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Preoperative and postoperative sperm parameter values from infertile men with varicocele were analyzed by computer-aided sperm analysis (CASA) to assess if sperm characteristics improved after varicocelectomy. Semen samples of men with proven fertility (n = 38) and men with varicocele-related infertility (n = 61) were also analyzed. Conventional semen analysis was performed according to WHO (2010) criteria and a CASA system was employed to assess kinetic parameters and sperm concentration.

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