Publications by authors named "P Castillo-Grau"
Article Synopsis
- LPAC (Low Phospholipid-Associated Cholelithiasis) is a rare genetic syndrome that contributes to biliary diseases, and its treatment with bile salts can prevent symptoms and surgeries.
- A study conducted from February 2021 to September 2022 identified 36 LPAC patients, indicating an incidence rate of 2.5% among hospital admissions for biliary causes, with higher rates in younger patients and women.
- Correctly diagnosing LPAC using straightforward criteria could reduce unnecessary hospital admissions and surgeries, particularly in women under 50 experiencing biliary issues.
Introduction: data on the prevalence and characteristics of hepatitis C patients lost to follow-up are lacking. In addition, the identification of this population clashes with data protection regulations.
Methods: the identification and contact protocol was submitted to the Health Care Ethics Committee.
Article Synopsis
- * Researchers applied a new testing protocol to analyze samples from 220 patients across various Spanish hospitals, finding that 88.6% had at least one RAS, with specific patterns linked to different HCV subtypes.
- * The findings reveal that certain patients had RAS not affected by the drugs they received, indicating the necessity for thorough RAS testing, especially since ribavirin treatment did not impact RAS diversity or type.
Objective And Methods: an observational, longitudinal, prospective study was performed to assess changes in perceived quality of life in asymptomatic patients with hepatitis C under treatment with direct-acting antivirals. Questionnaires SF-36 and EQ-5D-5L were administered to 86 treated patients and 12 controls.
Results: there were improvements in several parameters such as physical functioning, bodily pain, general health, vitality and social functioning, particularly when the perceptions were compared before treatment and after treatment completion and following recovery.