Publications by authors named "P Caropreso"
Background & Aims: Nephrotoxicity of intravenous iodinated contrast media (ICM) in cirrhosis is still a debated issue, due to scarce, low-quality and conflicting evidence. This study aims to evaluate the incidence and predisposing factors of acute kidney injury (AKI) in patients with cirrhosis undergoing contrast-enhanced computed tomography (CECT).
Methods: We performed a prospective, multicenter, cohort study including 444 inpatients, 148 with cirrhosis (cohort 1) and 163 without cirrhosis (cohort 3) undergoing CECT and 133 with cirrhosis (cohort 2) unexposed to ICM.
Article Synopsis
- The kappa index (K-Index) measures intrathecal immunoglobulin synthesis using a specific ratio of cerebrospinal fluid (CSF) and serum markers, but there's little data on how consistent these measurements are across different labs.
- In a study involving 15 paired CSF and serum samples analyzed by eight laboratories, there was excellent agreement in CSF KFLC measurements and good agreement in serum KFLC across different testing methods.
- The concordance for positive K-Index results was substantial overall and very good among certain laboratories, indicating that patients are unlikely to receive conflicting results regarding K-Index positivity despite variations in testing techniques.
This study assessed the periodontal conditions of type 2 diabetes (T2DM) patients attending an Outpatient Center in North Italy and explored the associations between metabolic control and periodontitis. Periodontal health of 104 T2DM patients (61 men and 43 women, mean age of 65.3 ± 10.
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- The study focuses on hepatic ischemia-reperfusion injury (IRI), a common issue in liver transplants and surgeries, and explores the protective potential of human liver stem cell-derived extracellular vesicles (HLSC-EV) against this injury in mice.* -
- In the experiment, HLSC-EV were administered after a period of induced IRI, and results showed that a specific lower dose (3 × 10 particles) significantly reduced liver damage, inflammation, and enzyme release compared to control groups.* -
- However, using a higher dose of HLSC-EV (7.5 × 10 particles) did not improve outcomes, indicating that there is an optimal dosage for effectiveness, and exceeding this