Publications by authors named "P C van de Woestijne"
Several techniques for the surgical correction of congenital supravalvular aortic stenosis have been devised. We describe the step-by-step surgical approach of a slide aortoplasty to correct localized supravalvular aortic stenosis in a 3-year-old child with Williams syndrome.
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- The study assessed the long-term clinical outcomes of patients who underwent an arterial switch operation (ASO) for transposition of the great arteries (TGA), highlighting a growing patient population.
- Findings indicated that at age 35, the survival rate was high at 93%, but a significant percentage (36%) required re-interventions, particularly affecting the right ventricular outflow tract.
- The research concluded that while survival rates are favorable, continuous monitoring and potential interventions are necessary throughout the patients' lives, with specific subtypes of TGA presenting higher risks for complications.
Human bone marrow permanently harbors high numbers of neutrophils, and a tumor-supportive bias of these cells could significantly impact bone marrow-confined malignancies. In individuals with multiple myeloma, the bone marrow is characterized by inflammatory stromal cells with the potential to influence neutrophils. We investigated myeloma-associated alterations in human marrow neutrophils and the impact of stromal inflammation on neutrophil function.
View Article and Find Full Text PDFObjectives: Congenital supravalvular aortic stenosis (SVAS) is a rare form of congenital outflow tract obstruction and long-term outcomes are scarcely reported. This study aims to provide an overview of outcomes after surgical repair for congenital SVAS.
Methods: A systematic review of published literature was conducted, including observational studies reporting long-term clinical outcome (>2 years) after SVAS repair in children or adults considering >20 patients.
Objectives: To support clinical decision-making in children with aortic valve disease, by compiling the available evidence on outcome after paediatric aortic valve repair (AVr).
Methods: A systematic review of literature reporting clinical outcome after paediatric AVr (mean age at surgery <18 years) published between 1 January 1990 and 23 December 2021 was conducted. Early event risks, late event rates and time-to-event data were pooled.