In experimental pain studies involving animals, subjective pain reports are not feasible. Current methods for detecting pain-related behaviors rely on human observation, which is time-consuming and labor-intensive, particularly for lengthy video recordings. Automating the quantification of these behaviors poses substantial challenges.
View Article and Find Full Text PDFTraumatic tendon injuries generate reactive oxygen species and inflammation, which may account for slow or poor healing outcomes. Selenium is an essential trace element presented in selenoproteins, many of which are strong antioxidant enzymes. Selenium nanoparticles (SeNPs) have been reported to promote tissue repair due to their anti-oxidative, anti-inflammatory, anti-apoptotic, and differentiation-modulating properties.
View Article and Find Full Text PDFPsychol Health
November 2024
Front Med (Lausanne)
October 2024
Aims: Obesity increases tendinopathy's risk, but its mechanisms remain unclear. This study examined the effect of high-fat diet (HFD)-induced obesity on the outcomes and inflammation of collagenase-induced (CI) tendon injury.
Methods: Mice were fed with standard chow (SC) or HFD for 12 weeks.