Publications by authors named "P C Panus"
Comparison of pharmacists' scoring of fall risk to other fall risk assessments.
J Am Pharm Assoc (2003)
May 2022
Objectives: Given their professional education and participation within the health care system, pharmacists are ideal candidates to assess drug-associated fall risk for patients. The purpose of this investigation was to determine whether pharmacists can quantitatively differentiate individuals who reported falling within the previous year (fallers) from those who do not (nonfallers), and to compare the pharmacists' evaluation with 2 recently published fall risk assessments.
Design: Cross-sectional design of pharmacists' assessments of fall risk.
Article Synopsis
- * Participants who engaged in treadmill gait training with visual feedback showed a significant reduction in their Quantitative Drug Index (QDI) scores, indicating a decrease in drug-associated fall risk, compared to those who trained without feedback.
- * The results also suggested that age played a significant role in how QDI scores changed, highlighting the need for further research to identify which specific drugs or classes contributed to this improvement.
Background: the development of an objective and comprehensive drug-based index of physical function for older adults has the potential to more accurately predict fall risk.
Design: the index was developed using 862 adults (ages 57-85) from the National Social Life, Health, and Aging Project (NSHAP) Wave 1 study. The index was evaluated in 70 adults (ages 51-88) from a rehabilitation study of dizziness and balance.
Article Synopsis
- - The study investigates how drugs affect mobility and balance in older adults and suggests using a quantitative drug index (QDI) to better assess fall risk.
- - Fifty-seven community-dwelling older adults participated, and various tests were conducted to measure mobility, balance, and other factors, including drug intake and body mass index (BMI).
- - Findings revealed that age, BMI, and QDI significantly influenced mobility and balance test scores, with those taking higher-impact drugs performing worse than those taking low-impact drugs.
Objective: Nonsteroidal anti-inflammatory drugs (NSAIDs) are assembled into two categories; cyclooxygenase (COX-1) sparing inhibitors of COX-2 and non-selective NSAIDs. Diclofenac (DICLO) is a non-selective NSAID that has been linked to serious side effects including gastric ulcers and renal injury. In this study, we examine the effect of poly(lactic-co-glycolic) acid nanoformulation on DICLO-associated adverse events and pharmacokinetics using a nanoparticle (NP) formulation previously developed in our laboratory.
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